COVID-19: Mix and match coronavirus vaccine trial results to be available by summer – By Thomas Moore (SKY News) / Feb 4 2021
Participants could get one dose of AstraZeneca’s jab and the second from Pfizer – an approach known as heterologous boosting.
Results of a world-first study that will mix and match COVID-19 vaccines are expected by the summer, according to a senior member of the research team.
Volunteers are to be recruited from today for the study, with more than 800 people over the age of 50 being asked to help.
The trial will compare the effect of giving a dose of the AstraZeneca/Oxford vaccine followed a few weeks later by the Pfizer/BioNTech jab – or vice versa.
All trials use different criteria for what counts as an infection which can lead to variations in results for effectiveness. However, all vaccines will reduce hospitalisations and deaths
The interval between the doses will be either four or 12 weeks to test whether giving the immune response a longer time to mature can improve the result.
