Research: No Consistent Link Between Paxlovid and COVID-19 Rebound – By Cecelia Smith-Schoenwalder (US News) / Dec 21, 2023
Researchers found that COVID-19 rebound happens to people whether they take antiviral treatments or not.
The findings underscore the benefits of COVID-19 treatments – especially as more Americans fall behind on their recommended coronavirus shots due to many reasons, including vaccine fatigue and hesitancy, which is often politically motivated.
In a report published Thursday by the Centers for Disease Control and Prevention, researchers looked at studies on COVID-19 rebound – or the resurgence of mild illness about three to seven days after resolution of the initial illness – published from 2020 through 2023. They found that the rebound effect happens to people whether they take COVID-19 treatments or not.
A person’s risk of rebound is related to many factors, including overall immune response to the coronavirus. No hospitalizations or deaths from COVID-19 rebound were reported in the studies.
“COVID-19 rebound might reflect viral fluctuation that is part of the natural disease process early in the course of illness and be related to how a person’s immune system responds to infection,” researchers wrote in a summary of the report.